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A case of the calcium pyrophosphate dihydrate (CPPD) deposition disease without condylar destruction of the temporomandibular joint
Author(s) -
Onodera Ken,
Ichinohasama Ryo,
Saito Masaji,
Ooya Klyoshi
Publication year - 1997
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1997.tb04552.x
Subject(s) - temporomandibular joint , condyle , anatomy , chondrocalcinosis , pathology , lesion , foreign body giant cell , giant cell , von kossa stain , medicine , chemistry , osteoarthritis , biochemistry , alkaline phosphatase , alternative medicine , enzyme
The case of caiclum pyrophosphate dihydrate (CPPD) deposition disease, which occurred at a rare site in the temporomandibular Joint (TMJ), is presented. A 48‐year‐old woman noted swelling in the preauricular area of her left cheek, which restricted her mouth opening. Radiological examination reveaied a radiopaque lesion in the posterior and medial area of the left space of the TMJ. During the opsration, the superior Joint space was entirely filled with a solid and whitish‐gray mass of chalky appearance. The lesion was partiy attached to the retrodiscal tissue without any destructive change around the condyle and mandibular form. Histological examination revealed the focl of amorphous crystalline material to contain rhomboidal, rod and needle shaped crystals, which had cartilaginous tissue in the dense fibrous background admixed with chronic inflammatory cells and foreign body‐type giant cells. The crystals were positive for von Kossa's stain and spectral peaks for phosphorus and caiclum were evident by electron probe microanalysis, thus suggesting the presence of CPPD.