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Ameloblastic fibrosarcoma arising de now in the maxilla
Author(s) -
Tajima Yoshifumi,
Utsumi Nobuo,
Suzuki Seiji,
Fujita Kuniya,
Takahashi Hiroshi
Publication year - 1997
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1997.tb04541.x
Subject(s) - pathology , maxilla , cytokeratin , vimentin , fibrosarcoma , calcification , lesion , dental alveolus , anatomy , immunohistochemistry , keratin , dystrophic calcification , cementum , medicine , biology , dentin , dentistry
An ameloblastlc fibrosarcoma (AFS) arlsing in the maxilla of a 14‐yearold male Is descrlbed. The tumor orlglnated from the alveolar bone of the right maxllia with no apparent history of pre‐exlstlng leslon. Histologically, the lesion was composed of benign‐appearlng epithelial Islands and strands scattered within an exceedingly cellular mass of mesenchymet tissue comprislng 8 large number of steliate‐and spindle‐shaped fibroblast‐like cells with marked pleomorphlsm. Occasional cementum‐like calcification was also noted. Immunohistochemically, the neoplastlc mesenchymal cells were positive only for vimentln, whereas the ameioblast‐like epithelial component showed a dlstlnctly positive reactlon for wide‐spectrum keratin and squamous cytokeratin. Clinicopathological features of the current case, as well as previously reported examples of AFS originating from the maxilla, are briefly discussed.