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Relapsing hemorrhagic varicella
Author(s) -
Suwabe Hisako,
Yabe Hiromasa,
Tsutsumi Yutaka
Publication year - 1996
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1996.tb03661.x
Subject(s) - pathology , medicine
A15 year old boy with a past history of chickenpox in infancy was complicated by lethal varicella during the course of chemotherapy against recurrent acute myeloblastic leukemia. He had received allo‐bone marrow transplantation and had overcome a graft‐versus‐host disease. The skin eruptions were hemorrhagic and progressive during the last 3 weeks, with numerous intranuclear inclusions histologically confirmed in the involved epidermis, hair follicles and endothe‐lial cells. lmmunohistochemical and electron microscopic studies confirmed the infection of varicella‐zoster virus.