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Malignant fibrous histiocytoma of the pancreas
Author(s) -
Haba Reiji,
Kobayashi Shoji,
Hlrakawa Eiichiro,
Miki Hiroshi,
Okino Takeshi,
Kurokawa Tatsuo,
Yamamoto Syuu
Publication year - 1996
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1996.tb03647.x
Subject(s) - vimentin , pathology , histiocyte , giant cell , pancreas , medicine , metastasis , immunohistochemistry , cancer , endocrinology
An extremely rare case of malignant fibrous histiocytoma In the pancreas Is reported. A 70‐year‐old man complained of upper abdominal discomfort. A tumor in the head of the pancreas was demonstrated by ultrasonography and computed tomography. The surgical specimen revealed a relatively well demarcated tumor, 9 × 7 × 6.5cm in size. Microscopically, fibroblastic, histiocytic, and muitinucleated giant tumor cells were observed in the myxoid area, but some tumor cells had proliferated in a storiform‐pleomorphlc pattern. Immunohtstochemically, some tumor cells were positive for lysozyme, α‐1‐antitrypsin, α‐1‐antichymotrypsin, and vimentin. Electron microscopically, tumor cells showed a combination of fibroblastic and histiocytic features. The patient Is currently well with no evidence of recurrence or metastasis 22 months after operation.