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Malignant fibrous histiocytoma of the esophagus
Author(s) -
Naganuma Hiroshl,
Ohtani Haruo,
Sayama Junzo,
Sakai Nobumitu,
Taira Yukio,
Shibuya Daisuke,
Miyazaki Atushi,
Sakurada Hiroyuki
Publication year - 1996
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1996.tb03638.x
Subject(s) - vimentin , pathology , esophagus , cd68 , immunohistochemistry , differential diagnosis , giant cell , desmin , anatomy , biology , medicine
A 78‐year‐old man presented with an esophageal polyp that was confirmed by Immunohistochemistry and electron microscopy to be malignant fibrous histiocytoma. The tumor was comprised of a proliferation of spindle‐shaped cells admixed with bizarre giant cells. These tumor cells were immunoreactive for smooth muscle actin, vimentin, α‐1‐arrti‐chymotrypsin and CD68. Electron microscopic examination revealed the myoflbroblastic and histtocytic features of the tumor cells. No elements of epithelial or myogenic differentiation were found in the tumor. Malignant fibrous histiocytoma of the esophagus is extremely rare, with 10 cases being documented so far in the literature. The differential diagnosis of pteomorphic tumors of the esophagus is discussed.