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Mouse mammary tumor virus and mammary tumorigenesis in wild mice
Author(s) -
Imal Shunsuke
Publication year - 1996
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1996.tb03570.x
Subject(s) - mouse mammary tumor virus , carcinogenesis , mammary tumor , biology , virus , virology , mammary gland , breast tumor , transmission (telecommunications) , cancer , cancer research , breast cancer , pathology , medicine , genetics , electrical engineering , engineering
The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV. Finally, the viral etiology of human breast cancer will be discussed.