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Protein‐losing enteropathy due to intestinal lymphangiectasia accompanied by mesenteric lymph node fibrosis
Author(s) -
Nakano Shigeo,
Kuramochi Shigeru,
Hosoda Yasuhiro,
Miura Soichiro
Publication year - 1996
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1996.tb03562.x
Subject(s) - enteropathy , lymphatic system , medicine , protein losing enteropathy , pathology , lymph node , lymph , fibrosis , edema , autopsy , lymphangiectasia , lymphatic vessel , cancer , metastasis , disease
An autopsy case of a 74‐year‐old man suffering from edema In the legs and diagnosed as protein‐losing enteropathy due to intestinal lymphanglectasla Is presented. He underwent a radlcal operatlon and radiotherapy for esophageal carcinoma at age 65 years and the onset of proteln‐losing enteropathy was at age 70. Postmortem examination disclosed widespread abnormalities of the duodenal and small intestinal lymphatics and mesenteflc lymph node flbmsls. The mucosal lymphatic capillaries were markedly dilated. In the sub‐mucosal and serosal layers, the lymphatic vessels showed marked dilatation in some areas and fibrous occlusion with very thick muscle layers in others. All these lymphatic changes were presumed to be attributable to a reactive process secondary to lymph congestion, which it is suggested, was caused by the mesenteric lymph node fibrosis.