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Correlation between angiographic features and pathologic changes in breast carcinoma
Author(s) -
Ishige Hideo,
Takazawa Hiroshi,
Shiramatsu Kazuyasu,
Sasaki Norihide,
Nakajima Nobuyuki,
Kondo Yoichiro
Publication year - 1994
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1994.tb02601.x
Subject(s) - medicine , pathology , infiltration (hvac) , stromal cell , fibrosis , breast cancer , breast carcinoma , carcinoma , cancer , physics , thermodynamics
The correlation between angiographic tumor blushing and underlying pathologic factors was studied. Twenty female patients with breast cancer were divided into three groups according to the degree of tumor blushing. Primary tumors were divided into three areas: marginal, central and intermediate areas. In each area, the number of biood vessels per 10 4 μ 2 as randomly counted in 10 fields and a mean value of vessels was compared among the three groups. It was found that the following pathologic findings were significantly related to strong angiographic staining: (i) well‐circumscribed border; (ii) large tumor nest; (iii) severe inflammatory ceil infiltration; (iv) mild stromal fibrosis; and (v) absence of lymph node metastasis. The mean value of blood vessels in the strongly positive group was significantly increased in the overall and the intermediate areas. The density of the vessels in the intermediate area was thus thought to be responsible for the tumor blushing.