Open AccessCardiac Rupture Complicating Hemorrhagic Infarction after Intracoronary Thrombolysis
Author(s) -
IshibashiUeda Hatsue,
Imakita Masami,
Fujita Hirotaka,
Katsuragi Michiaki,
Yutani Chikao
Publication year - 1992
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1992.tb03096.x
Subject(s) - medicine , thrombolysis , myocardial infarction , cardiac rupture , hemopericardium , cardiology , chest pain , autopsy , urokinase , infarction , cardiac tamponade
An 80‐year‐old woman with acute myocardial infarct intracoronary thrombolysis by a large dose of urokinase four hours after the onset of chest pain. Despite the patient having no chest pain after intracoronary thrombolysis and her general condition being stable, she died suddenly on the 4th hospital day. Autopsy revealed hemopericardium due to cardiac rupture, which occurred at the center of the transmural hemorrhagic infarction of the anteroseptal wall. The massive hemorrhagic infarction was promoted by reperfusion from thrombolytic therapy. She had also classic risk factors for cardiac rupture, such as hypertension, senility, female gender, and first acute myocardial infarct. Therefore, the present case demonstrated that hemorrhagic infarction increased the incidence of cardiac rupture.