Open AccessVasculitis and Pyrexia Associated with Superficial Spreading Gastric Carcinoma
Author(s) -
Akikusa Bunshiro,
Harihara Yasushi,
Nagato Yoshinobu,
Nobori Masakazu
Publication year - 1992
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1992.tb02544.x
Subject(s) - medicine , pathology , antrum , gastric carcinoma , vasculitis , lymph , carcinoma , adenocarcinoma , gastric antrum , stomach , cancer , disease , gastroenterology
A case of low grade fever developing about a month before the discovery of gastric carcinoma is reported. No findings of infection or collagen disease were revealed. The fever continued for about 3 months, but promptly disappeared after surgical removal of the tumor. A superficial spreading mucosal carcinoma with minimal invasion to the sub‐mucosa was seen in the antrum, showing the features of poorly differentiated adenocarcinoma. In addition, unique venous inflammation was recognized beneath and around the neoplasm. Arteries and lymph vessels did not exhibit any inflammatory changes. It was presumed that the gastric carcinoma had induced phlebitis, which subsequently brought about the fever. As to the pathogenetic mechanism, it was suggested that a substance produced by the carcinoma cells flowed into nearby veins to induce the phlebitis. Acta Pathol Jpn 42 : 293‐297, 1992.