Open AccessA Clinicopathologic Study of Tumors and Tumor‐like Lesions of the Penis
Author(s) -
Hayashi Tomayoshi,
Tsuda Nobuo,
Shimada Osamu,
Kishikawa Masao,
Iseki Masachika,
Nishimura Naoki,
Taniguchi Keisuke,
Saito Yutaka
Publication year - 1990
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1990.tb01571.x
Subject(s) - penis , pathology , medicine , anatomy
A total of 147 specimens from 93 patients with penile lesions were examined at Nagasaki University Hospital during a 27‐year period from 1961 to 1987. The most frequent malignant tumor was squamous cell carcinoma (SCC, 33 cases, 35.5%), followed by extramammary Paget's disease, transitional cell carcinoma, and Bowen's disease. The benign tumors and tumor‐like lesions included condylorna acuminatum, cyst of the genitoperineal raphe, and lymphangioma. SCC of the penis accounted for less than 0.1% of all specimens and less than 0.62% of malignant tumors in men filed at our hospital. True phimosis accompanied 81.5% of the SCC cases. The 5‐and 10‐year survival rates for SCC were 77.2% and 71.3% respectively. Two patients died of penile SCC. It was considered that an absence of both keratohyaline granules in the granular layer and melanin pigment in the basal layer can serve as a useful histologic indicator for diagnosis of well differentiated SCCs that are otherwise difficult to identify.