Open AccessEosinophilic Neuronal Inclusion Bodies in the Temporal Lobe
Author(s) -
Kojima Hideaki,
Nagashima Kazuo,
Tokunaga Hidehiro,
Takahashi Kiyoshi,
Etoh Mitsuaki
Publication year - 1990
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1990.tb01545.x
Subject(s) - inclusion bodies , eosinophilic , pathology , anatomy , temporal lobe , inclusion (mineral) , lobe , biology , nucleus , chemistry , neuroscience , medicine , mineralogy , biochemistry , escherichia coli , epilepsy , gene
Intracytoplasmic neuronal inclusion bodies were found in the temporal lobe of an elderly woman. The oval or rod‐shaped inclusion bodies were eosinophilic, showed bright red staining with azan, and were about half the size of the nucleus of a large neuron. They were non argyrophilic and non congophilic. Ultrastructurally, the inclusion bodies consisted of aggregates of filamentous materials showing partial periodicity. Among inclusion bodies reported up to now, the present ones resembled some described previously as “thalamic inclusions”, but were different with regard to their partial filament periodicity, and unusual in that they were located in the deep layer of the temporal lobe and not in the thalamic nuclei. Acta Pathol Jpn 40: 785‐791, 1990.