Open AccessGallstones in Gallbladder Diseases
Author(s) -
Yamamoto Masami,
Nakajo Susumu,
Tahara Eiichi
Publication year - 1989
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1989.tb02487.x
Subject(s) - gallstones , gallbladder , gastroenterology , medicine , incidence (geometry) , adenocarcinoma , metaplasia , adenoma , carcinoma , pathology , cancer , physics , optics
The correlation between gallbladder stones (gallstones) and various gallbladder diseases was examined. The incidence of gallstones was 47.1% in cases of nonneoplastic epithelial polyp, 48.0% in adenoma, and 59.1% in adenocarcinoma. There was no relation between the incidence of gallstones and sex. The incidence of gallstones in cancer cases showed no difference among histological gradings. Non neoplastic epithelial polyps, adenomas and carcinomas were divided into metaplastic type and non metaplastic type based on the presence or absence of metaplastic changes. Comparison of the incidence of gallstones showed that cases of metaplastic type polyp and adenoma had a higher incidence of gallstones than non metaplastic type polyp and adenoma. In the cases of cancer, no differences were observed in the incidence of gallstones between metaplastic type and non metaplastic type carcinomas. However, comparison among early carcinomas showed that metaplastic type carcinoma had a significantly higher incidence of gallstones than the non metaplastic type. These results suggest that gallstones may play an important role in the histogenesis of gallbladder diseases of the metaplastic type. Acta Pathol Jpn 39: 582 585, 1989.