Open AccessA Case of Malignant Rhabdoid Tumor Arising from Soft Parts in the Prepubic Region
Author(s) -
Tsujimura Takashi,
Wada Akira,
Kawano Kiyoshi,
Iwasa Atsushi,
Mizutani Syuutarou
Publication year - 1989
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1989.tb02416.x
Subject(s) - histogenesis , pathology , eosinophilic , keratin , cytoplasm , hyaline , lesion , intermediate filament , biology , staining , anatomy , immunohistochemistry , medicine , cell , microbiology and biotechnology , genetics , cytoskeleton
An extrarenal malignant rhabdoid tumor arising from soft parts in the prepubic region of a 37 year‐old man is described. This case appears to be unusual with regard to its location and age at onset. To our knowledge, the patient is the oldest recorded in whom such a lesion has arisen. Histologically, the tumor consisted of an admixture of polygonal and elongated cells with abundant eosinophilic cytoplasm frequently containing hyaline‐like globules. Ultrastructurally, these cytoplasmic inclusions were compatible with intermediate filaments. Immunohisto‐chemical staining disclosed keratin (non squamous epithelial type) and epithelial membrane antigen positivity. These characteristic features were identical to malignant rhabdoid tumor of the kidney seen in infants and young children. This extrarenal malignant rhabdoid tumor showed an aggressive clinical course, although its exact histogenesis was unclear. Acta Pathol Jpn 39: 677 682, 1989.