Open AccessAMELOBLASTOMA OF MUCOSAL ORIGIN *
Author(s) -
Takeda Yasunori,
Kuroda Masafumi,
Suzuki Atsumi
Publication year - 1988
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1988.tb02377.x
Subject(s) - ameloblastoma , pathology , keratin , epithelium , ultrastructure , lesion , basal (medicine) , biology , anatomy , adamantinoma , mixed tumor , basal cell , basal cell carcinoma , medicine , maxilla , endocrinology , insulin
Histopathological, histochemical and ultrastructural findings of an extraosseous ameloblastoma occurring in an 89‐year‐old woman are reported. Rete pegs of the gingival epithelium covering the lesion showed marked extension into the lesion, and direct continuity between the extended rete pegs and tumor follicles was evident. Ultrastructural examination showed that the rete pegs gradually became transformed into double‐stranded epithelial cords as they elongated deeply, and that the ends of these epithelial cords gradually became transformed into tumor follicles. These findings suggest that the potential for differentiation is maintained in the basal cells of the gingival epithelium throughout life, and can be triggered by unknown stimuli. The ultrastructure of the tumor follicles was similar to that of intraosseous follicular ameloblastoma, but was different from that of cutaneous basal cell carcinoma. Histochemical staining for keratin protein revealed that the central cells of tumor follicles and the covering epithelium were positive, whereas the peripheral cells of tumor follicles and the elongated rete pegs were negative. ACTA PATHOL JPN38: 1053∼1060, 1988.