Open AccessHEPATIC SQUAMOUS CELL CARCINOMA WITH HYPERCALCEMIA IN LIVER CIRRHOSIS
Author(s) -
Arase Yasuji,
Endo Yuzo,
Hara Mitsuru,
Kumada Hiromitsu,
Ikeda Kenji,
Yoshiba Akira
Publication year - 1988
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1988.tb02336.x
Subject(s) - pathology , keratin , cirrhosis , basal cell , monoclonal antibody , cytoplasm , immunofluorescence , autopsy , immunohistochemistry , medicine , carcinoma , hepatocellular carcinoma , antibody , biology , cancer research , immunology , biochemistry
Primary squamous cell carcinoma of the liver is exceedingly rare and has previously been reported in association with hepatic teratoma, hepatic cyst or hepatolithiasis. This paper describes an autopsy case of squamous cell carcinoma which developed with hypercalcemia in a cirrhotic liver. This cancer was characterized histologically, immunohistologically and ultrastructurally, and was found to exhibit immunofluorescence positivity for anti‐epidermal keratin monoclonal antibody, together with the presence of tonofllaments scattered sparsely in the cytoplasm of the cancer cells.