Open AccessPRIMARY MUCOSAL HYPERPLASIA OF THE GALLBLADDER
Author(s) -
Yamamoto Masami,
Nakajo Susumu,
Ito Masaki,
Tahara Eiichi
Publication year - 1988
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1988.tb02311.x
Subject(s) - gallbladder , hyperplasia , pathology , epithelium , medicine , enteroendocrine cell , cystic duct , endocrine system , gastroenterology , hormone
A case of primary mucosal hyperplasia of the gallbladder in a 55‐year‐old man is reported. Endoscopic ultrasonography demonstrated diffuse mucosal thickening of the gallbladder which was associated with anomalous union of the pancreatico‐biliary duct system. Histologically, the mucosa showed villous and spongioid hyperplasia. The mucosa, which consisted of tall columnar cells that were morphologically similar to ordinary gallbladder epithelium, showed no metaplastic changes such as occurrence of mucous glands, Paneth cells, goblet cells, endocrine cells, or lysozyme immunoreactivity. These findings suggested that this disease was based on hyperplasia of ordinary gallbladder epithelium.