Open AccessUNUSUAL CLEAR REGENERATIVE NODULES OF THE LIVER WITH ACCUMULATION OF ORCEIN AND VICTORIA BLUE‐POSITIVE GRANULES
Author(s) -
Haratake Joji,
Horie Akio,
Ishii Nobuyoshi,
MatSuo Norio,
Lee Sung Do
Publication year - 1988
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1988.tb01074.x
Subject(s) - orcein , pathology , anatomy , chemistry , medicine , staining
An unusual nodular transformation of the liver was found in a 53‐year‐old man with meningoencephalitis who died of brain stem herniation. Postmortem examination revealed marked neuronal ischemic changes and bronchopneumonia as well as meningoencephalitis. The liver showed no significant lesions macroscopically. Histologically, there were many small nodules, less than 1 mm in diameter and composed of clear hepatocytes, throughout the liver. The liver cells in these nodules showed mild hyperplastic changes. Many fine granules, stained by orcein and Victoria blue, were found exclusively in the hepatocytes of these nodules. We describe the peculiar histopathology of this case with reference to some related lesions. ACTA PATHOL JPN 38 : 83–88, 1988.