Open AccessDIFFUSE INTERSTITIAL PULMONARY FIBROSIS AND LUNG CANCER
Author(s) -
Kawai Toshiaki,
Yakumaru Kazuhiro,
Suzuki Minoru,
Kageyama Keizo
Publication year - 1987
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1987.tb03130.x
Subject(s) - pathology , medicine , lung cancer , pulmonary fibrosis , lung , fibrosis
Forty‐two cases of lung cancer complicated with diffuse interstitial pulmonary fibrosis (DIPF) were selected from 13,056 autopsy cases. They were divided into primary (Group I and II) and secondary (Group III) DIPF, and histopathologic and clinicopathologic studies were made. The prevalence of lung cancer with primary DIPF was 17% (8/47) which was significantly (p< 0.01) higher than that without DIPF (7% or 886/13,009). All eight cases of lung cancer in Group I and II were male, and 7 had cigarette‐smoking history. The anatomical sites of lung cancer and DIPF were all peripheral in origin, and in 7 cases located primarily in the lower lobes (left: right = 6: 1). Adenocar‐cinoma was the most common type. The study suggests that male DIPF patients with long clinical history should be followed thoroughly for lung cancer.