Open AccessULTRASTRUCTURAL STUDY OF LYMPHOCYTIC INTERACTION WITH HEPATOCYTES AND ENDOTHELIAL CELLS IN ACUTE NON‐A, NON‐B HEPATITIS
Author(s) -
Indue Osami,
Itakura Hideyo,
Toriyama Kan,
Satoh Akira,
Furukawa Ryuji,
Kusumoto Yukio,
Ishii Nobuko,
Koji Toshihiko,
Nagataki Shigenobu
Publication year - 1987
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1987.tb03056.x
Subject(s) - ultrastructure , pathology , medicine , biology
In the liver biopsy specimens of all six patients with acute non‐A, non‐B hepatitis, the lymphocytic interaction with hepatocytes and sinusoidal endothelial cells was observed by electron microscopic study. Lymphocytes were in a close contact with damaged hepatocytes and interrupted endothelial cells, and the microvilli on the surface of these damaged hepatocytes were degenerated and lost. These findings pointed out the possibility that the lymphocyte may play one of the important roles in hepatocytic damage and endothelial cell damage in acute non‐A, non‐B hepatitis.