Open AccessEXFOLIATIVE CYTOPATHOLOGY OF ALVEOLAR RHABDOMYOSARCOMA
Author(s) -
Nishikawa Akiyoshi,
Tanaka Takuji,
Kanai Nobuyuki,
Kato Kazuo,
Mori Hideki,
Takahashi Masayoshi
Publication year - 1987
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1987.tb00450.x
Subject(s) - pathology , cytopathology , alveolar rhabdomyosarcoma , eosinophilic , nucleolus , cytoplasm , immunoperoxidase , biology , rhabdomyosarcoma , anatomy , sarcoma , medicine , cytology , microbiology and biotechnology , antibody , immunology , monoclonal antibody
Exfoliative cytopathology of alveolar rhabdomyosarcoma is presented. A 34‐year‐old male was found to have alveolar rhabdomyosarcoma of the retroperitoneum at autopsy. Ascites was recognized in the course of this disease. Cytological features in the ascites were characterized by relatively small‐sized ovoid cells observed singly or in loose clusters. The neoplastic cells possessed small amount of rather vesicular cytoplasm and an eccentric nucleus. The nucleus characteristically revealed multiple deep indentations in the nuclear membrane, a few prominent eosinophilic nucleoli and finely granular or evenly distributed chromatin pattern. These cytological findings, especially the nuclear features, might be useful to differentiate alveolar rhabdomyosarcoma from other neoplasms which consist of relatively small‐sized ovoid cells even if the striated muscle origin cannot be confirmed by immunoperoxidase staining.