Open AccessPRIMARY PULMONARY HYPERTENSION
Author(s) -
Fujinami Mutsuyo,
Morimoto Shinichiro,
Nishikawa Toshio,
Sato Akito,
Yamada Yukio,
Kajita Akira
Publication year - 1987
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1987.tb00374.x
Subject(s) - primary (astronomy) , pulmonary hypertension , pathology , medicine , cardiology , astronomy , physics
Eight autopsy cases of primary pulmonary hypertension were studied. All cases were diagnosed as primary plexogenic arteriopathy. Microscopical study of the lungs showed in every case hypertensive arterial changes of Grade II‐VI after Heath & Edwards' criteria. Truncal pulmonary artery of three cases revealed aneurysm or severe dilatation with thrombus, and dilation was also recorded in another three cases. Histology of gross pulmonary artery in several cases presented disruption and defect of elastic fiber and alcian‐blue positive microcystic change in media, lymphoid cell infiltration in outer media and inner adventitia, adventitial thickening, and intimal fibrosis. The liver of 7 cases showed secondary congestive changes and in one case intrahepatic portal vasculitis.