Open AccessCARCINOSARCOMA OF THE GALLBLADDER: Report of a Case and Review of the Literature
Author(s) -
Inoshita Shunichi,
Iwashita Akinori,
Enjoji Munetomo
Publication year - 1986
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1986.tb03124.x
Subject(s) - carcinosarcoma , gallbladder , medicine , pathology , general surgery , carcinoma , gastroenterology
An extremely rare case of carcinosarcoma of the gallbladder is reported. The tumor presenting as a large, soft polypoid growth was microscopically characterized by an admixture of adenocarcinomatous and sarcomatous ele‐ments, the latter containing specific heterologous mesenchymal elements such as osteoid, cartilage, and rhabdomyoblasts. The cytoplasm of neoplastic rhabdomyoblasts offered unequivocal cross striations and was strongly posi‐tive for myoglobin, determined by the immunoperoxidase procedure. Metas‐tatic tumors in the liver also exhibited a dual composition of adenocarcinoma and rhabdomyosarcoma. This appears to be the second documented case of this type of neoplasm with the rhabdomyosarcomatous component. The clinical settings and morbid prognosis were similar to events in cases of carcinoma of the gallbladder.