Open AccessCLEAR CELL CHONDROSARCOMA: A Report of Two Cases and Review of Literature
Author(s) -
Yamaguchi Hideo,
Isu Kazuo,
Ubayama Yuji,
Yamawaki Shinya,
Gotoh Mamoru,
Miyagawa Akira,
Minami Akio,
Matsuno Takeo,
Sasaki Tesuto,
Nojima Takayuki
Publication year - 1986
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1986.tb02829.x
Subject(s) - pathology , cytoplasm , lytic cycle , chondrosarcoma , lesion , femur , medicine , nucleus , anatomy , biology , surgery , microbiology and biotechnology , virus , virology , psychiatry
Two cases of clear cell chondrosarcoma located in the distal femur and proximal humerus are reported. Both patients were men aged 35 and 51 years. Their initial symptom was a pathologic fracture. Roentgenographically, one patient showed a purely lytic lesion and another lytic with centrally radiodensity. Microscopic examination revealed that the tumor cells have a centrally placed vesicular nucleus surrounded by a clear cytoplasm, with distinct boundaries. Their cytoplasm stained with S‐100 protein by the peroxidaseantiperoxidase method. We found 36 reported cases (including the two reported here), and delineated the clinico‐pathologic characteristics of the disease. ACTA PATHOL. JPN. 36: 1577‐1585, 1986.