Open AccessINGUINAL SWEAT GLAND CARCINOMA WITH CHORIOCARCINOMATOUS DIFFERENTIATION
Author(s) -
Nashiro Kazutaka,
Iwamasa Teruo,
Maeyama Masao
Publication year - 1986
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1986.tb01052.x
Subject(s) - sweat gland , alkaline phosphatase , pathology , carcinoma , radiation therapy , eccrine sweat gland , biology , medicine , sweat , enzyme , biochemistry
An inguinal sweat gland carcinoma is described including the unusual occurrence of αhCG. The αhCG was demonstrated in the tumor presenting choriocarcinomatous differentiation and undifferentiated polygonal cells in ordinary tumor nests. βhCG and SP‐1 were weakly and sporadically demonstrated in a small area of the tumor presenting choriocarcinomatous differentiation. On the other hand, hPL and histochemical reaction of placental type alkaline phosphatase were not observed in the choriocarcinomatous and undifferentiated tumor cells. CEA was observed in both ordinary sweat gland carcinoma nests and choriocarcinomatous differentiated regions. In the ordinary tumor nests, enzyme histochemical reactions of phosphorylase and SDH were positive. And S 100 protein was sporadically demonstrated. In spite of chemotherapy and radiotherapy, the patient died after a short duration of the disease. ACTA PATHOL. JPN. 36: 621–630, 1986.