Open AccessMULTIPLE PRIMARY MALIGNANT FIBROUS HISTIOCYTOMA OF THE STOMACH AND SMALL INTESTINE
Author(s) -
Shibuya Hiroyuki,
Azumi Norio,
Onda Yoshikazu,
Abe Fumihiko
Publication year - 1985
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1985.tb02214.x
Subject(s) - stomach , curvatures of the stomach , jejunum , small intestine , pathology , gastrectomy , antrum , medicine , immunoperoxidase , ileus , large intestine , anatomy , gastroenterology , cancer , immunology , monoclonal antibody , antibody
A case of multicentric malignant fibrous histiocytoma of the stomach and small intestine is reported. The patient was a 60‐year‐old man who had total gastrectomy under an impression of a gastric carcinoma. The resected stomach revealed a large polypoid mass in the antral portion at the greater curvature. Three months later, he developed ileus and an 80 cm segment of the jejunum was removed. It contained two polypoid masses identical to that seen in the stomach. The tumors showed, in addition to the characteristic light microscopic appearances, strong positivity for alpha‐1‐antitrypsin by an immunoperoxidase technique, indicating the diagnosis of malignant fibrous histiocytoma (MFH). Electron microscopic findings were also consistent with MFH. We believe that this is the first well‐documented case of MFH arising from the stomach and small intestine, to the best of our knowledge.