Open AccessLECTIN HISTOCHEMISTRY IN A CASE OF ULCERATIVE COLITIS COMPLICATING RECTAL CARCINOMA
Author(s) -
Yonezawa Suguru,
Nakamura Takao,
Tanaka Sadao,
Kuroki Katsuro,
Sato Eiichi
Publication year - 1985
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1985.tb01454.x
Subject(s) - peanut agglutinin , lectin , ulcerative colitis , pathology , ulex europaeus , immunohistochemistry , agglutinin , lesion , staining , carcinoma , epithelium , colonic carcinoma , medicine , biology , chemistry , microbiology and biotechnology , disease
The large bowel from a patient with ulcerative colitis complicating a rectal carcinoma was histochemically investigated by using two lectins; Ulex eur‐opaeus agglutinin‐I (UEA‐I) and peanut lectin (PNA). Much UEA‐I binding glycoantigen and PNA binding glycoantigen appeared in the carcinoma and dysplastic lesion, whereas only a small amount of both antigens was found in the non‐dysplastic regenerating epithelium. Consequently, a very sharp contrast between the dysplastic lesion and non‐dysplastic regenerating epithelium was demonstrated by the lectin staining. ACTA PATHOL. JPN. 35: 1571–1579. 1985.