Open AccessPLASMA CELL GRANULOMA OF THE LUNG WITH EXTRAPULMONAL EXTENSION
Author(s) -
Muraoka Shunji,
Sato Toshihiro,
Takahashi Tatsuro,
Ando Masakatsu,
Shimoda Akihisa
Publication year - 1985
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1985.tb00635.x
Subject(s) - plasma cell granuloma , pathology , connective tissue , myofibroblast , granuloma , plasma cell , lung , immunohistochemistry , reticular connective tissue , medicine , biology , chemistry , fibrosis , inflammatory pseudotumor , lesion , bone marrow
A rare case of plasma cell granuloma of the lung in a 5‐year‐old girl showing extrapulmonal extension to the adjoining thoracic wall was reported. Intrapulmonal and thoracic wall granulomas revealed the same histopathologic features; proliferation of plasma cells and fibrous connective tissue. Although slightly atypical plasma cells were observed among many mature ones, immunohistochemical examination revealed polyclonal proliferation, confirming their inflammatory nature. Cellular components of fibrous connective tissue were identified as fibroblastic cells and myofibroblasts by electron microscopy. The present case and literature suggested the importance of the fact that “infiltrative” plasma cell granuloma had a tendency to occur in children. ACTA PATHOL. JPN. 35: 933–944, 1985.