Open AccessFINGERPRINT‐LIKE STRAIGHT CRYSTALLOID MICROFILAMENTS IN LOBULAR GLOMERULONEPHRITIS
Author(s) -
Hamaya Kazuo,
Doi Kenji
Publication year - 1985
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1985.tb00618.x
Subject(s) - pathology , microfilament , fingerprint (computing) , medicine , glomerulonephritis , anatomy , chemistry , computer science , kidney , artificial intelligence , cytoskeleton , biochemistry , cell
This 64‐year‐old male presented edema and proteinuria. With increasing renal insufficiency and persistent fever, he died 7 months after the onset of illness, complicated with terminal miliary tuberculosis. All the glomeruli showed sclerotic nodular lobulation and mesangial circumferential interposition with positive immunoglobulin and complement predominantly along the capillary, consistent with lobular glomerulonephritis (LGN) or terminal stage of membranoproliferative glomerulonephritis (MPGN). Electron microscopy revealed subepithelial straight crystalloid microfilaments in the amorphous deposits. These structures possibly represent IgG or its fragment as a component of immune complex crystallized in some particular condition. ACTA PATHOL. JPN. 35 : 767–773, 1985.