
MALIGNANT GIANT CELL TUMOR OF TENDON SHEATH Report of a Case
Author(s) -
Ushijima Masahiro,
Hashimoto Hiroshi,
Tsuneyoshi Masazumi,
Enjoji Munetomo,
Miyamoto Yuichi,
Okue Akira
Publication year - 1985
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1985.tb00611.x
Subject(s) - pathology , tendon sheath , giant cell , medicine , tendon , anatomy
In a patient with pigmented villonodular synovitis of the right knee joint, there occurred a malignant giant cell tumor of tendon sheath. There was clinical evidence of metastasis after the second local recurrence and the recurrent tumors were studied enzyme cytochemically and electron microscopically. Ultrastructurally, the malignant tumor consisted of three principal cell types; histiocyte‐like cells, fibroblast‐like cells, and intermediate cells, with unique attendance of myofibroblasts. This may be the first report of the presence of myofibroblasts in malignant giant cell tumor of tendon sheath. Enzyme cytochemistry revealed various functional properties of histiocytes. ACTA PATHOL. JPN. 35 : 699–709, 1985.