Open AccessMonoclonal Igm‐Secreting Neoplasms Clinical and Morphologic Heterogeneity
Author(s) -
Nakamine Hirokazu,
Takenaka Toru,
Nishino Eisei,
Maeda Jiro,
Nishihara Toru,
Saito Koji,
Yabumoto Mitsuo,
Umemoto Masaaki,
Masuyama Yoshiaki,
Honda Hiroshi,
Yamamoto Junichi
Publication year - 1984
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1984.tb07642.x
Subject(s) - pathology , medicine , monoclonal , monoclonal antibody , antibody , immunology
Two patients with monoclonal IgM‐secreting neoplasms are presented. Though both patients could be diagnosed as Waldenström's macroglobulinemia, the clinicopathologic features were quite contrastive. Most neoplastic cells in Case 1 showed lymphocytic morphology with rather leukemic process, while those in Case 2 were highly polymorphic with solid proliferation. The clinical and morphologic heterogeneity in these cases and cases in the literature is discussed, and the possible requirement to establish a system for the subclassification of IgM‐secreting neoplasms is insisted.