Open AccessAn Ultrastructural and Histochemical Study of Alveolar Soft Part Sarcoma With Special Reference to The Nature of Crystals
Author(s) -
Kamei Toshiaki,
Ishihara Tokuhiro,
Yamashita Yoshimi,
Takahashi Mutsuo,
Uchino Fumiya,
Ishizaka Hiroaki,
Moroki Ziro,
Ueda Naoki
Publication year - 1984
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1984.tb07572.x
Subject(s) - alveolar soft part sarcoma , pathology , ultrastructure , soft tissue , acid phosphatase , lesion , metastasis , sarcoma , biology , anatomy , medicine , cancer , enzyme , biochemistry
We have presented a case of typical alveolar soft part sarcoma probably originating from the soft tissues of the retroperitoneum with metastasis to the brain. An ultrastructural study including histochemical observation of the metastatic lesion was performed to clarify the nature of the crystals characteristic to the tumor cells of this disease. The crystalline structures have acid‐phosphatase activtiy at a histological and ultrastructural level. Our results suggested that they might be derived from coalescence of primary lysosomes or by digestive disintegration of some protein.