Open AccessDUODENAL SOMATOSTATINOMA Immunohistopathology and Review of Literature
Author(s) -
Kaneko Hiroshi,
Toshima Muneatsu,
Kobayashi Hiroshi,
Kitazawa Mikio,
Ito Seiki,
Iwanaga Toshihiko,
Kusumoto Yoshisuke,
Fujita Tsuneo,
Nitta Hiroshi
Publication year - 1983
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1983.tb02108.x
Subject(s) - argentaffin , somatostatin , medicine , epigastric pain , gastroenterology , pathology , duodenum , radioimmunoassay , adenocarcinoma , cancer , vomiting
A case of duodenal somatostatinoma is reported. The patient, a 54‐year‐old male, had complained of an epigastric pain due to gastric ulcer and a duodenal polyp was unexpectedly found at a gastrectomy. The polyp showed basically tubular adenocarcinoma, with negative argyrophil and argentaffin reactions. By an indirect immunofluorescent examination almost all of the tumor cells were revealed as somatostatin‐immunoreactive. Big somatostatin was also positive. Radioimmunoassay of the tumor indicated 6400 pg of somatostatin‐like immunoreactivity per milligram of wet tissue. This seems to be the second case of duodenal somatostatinoma, following the case reported by us previously.