Open AccessGLOMERULAR TISSUE INJURY IN IgA NEPHRITIS
Author(s) -
SHIGEMATSU Hidekazu,
KOBAYASHI Yutaka,
TATBNO Sumio,
HIKI Yasuyuki,
KUWAO Sadahito
Publication year - 1983
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1983.tb01424.x
Subject(s) - lesion , nephritis , pathology , glomerular basement membrane , medicine , basement membrane , glomerulus , glomerulonephritis , kidney
The glomerular lesions In 129 cases of IgA nephritis were analyzed. The development of glomerular injury occurred in two ways, one being a chronic mesangial depositive and sclerosing lesion commonly found in most glomeruli, and the other an acute but local injury initiating from the local peripheral glomerular basement membrane abnormality, i.e., thinning and/or splitting, which was seen at least in one third of all cases. The activation of the local coagulatory process could add segmental glomerular changes including small crescents, adhesion, and local tuft necrosis to the mesangial lesion. ACTA PATHOL. JPN. 33; 367–380, 1983.