Open AccessPRIMARY YOLK SAC TUMOR OF THE LIVER
Author(s) -
Natori Takashi,
Teshima Shinichi,
Kikuchi Yuko,
Aizawa Miki,
Konno Tetsuro,
Tamaki Akira,
Kakita Akira,
Shinada Yoshihide,
Kasai Yoichi
Publication year - 1983
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1983.tb00362.x
Subject(s) - pathology , yolk sac , immunohistochemistry , uterus , autopsy , sinusoid , basement membrane , stomach , peritoneum , biology , cytoplasm , anatomy , medicine , embryo , biochemistry , genetics , microbiology and biotechnology
An autopsy case of yolk sac tumor of the liver in a 29‐year‐old female was reported. The tumor was found originally in the right anterior segment of the liver on the first operation. The autopsy disclosed that the liver was almost entirely replaced by multiple, round tumor nodules. The tumor masses continuously extended to the peritoneum and to the subcutaneous tissue. There were no tumors in other organs including the ovaries, gut, stomach, lung, uterus, and kidneys, indicating that the tumor originated in the liver. Microscopically, the tumor showed typical characteristics of the yolk sac tumor. An immunohistochemical study showed that AFP was distributed fine granularly in the cytoplasm of tumor cells. Electron microscopic observation disclosed large amounts of electron‐dense material being closely related to basement membrane.