Open AccessNODULAR HYPERPLASIA WITH A CENTRAL TELANGIECTATIC FIBROSIS IN THE LIVER OF NON‐CIRRHOTIC PORTAL FIBROSIS (IDIOPATHIC PORTAL HYPERTENSION)
Author(s) -
Nakanuma Yasuni,
Wada Michiko,
Haratake Joji,
Ohta Goroku
Publication year - 1982
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1982.tb02090.x
Subject(s) - pathology , medicine , hyaline , fibrosis , portal hypertension , focal nodular hyperplasia , cirrhosis , hyperplasia , gastroenterology , hepatocellular carcinoma
Unusual nodules of hyperplastic hepatocytes were found In the liver of a 64‐year‐old woman with non‐cirrhotlc portal fibrosis (idiopathic portal hypertension). These nodules were subdivded by stellate fibrous tissues which, in the center of the nodules, contained conspicuous telangiectatic lesions with congestion. The latter was consisted of markedly dilated sinusoids and fibrosis of their walls either in a lack of hepatocytes or with severly atrophic hepatic column. The lesions were different from already described focal nodular lesions in the liver. No drugs and chemicals could be identified as the causative agents. The small arterial changes, namely, hyalinization and thickening of their walls and luminal narrowing or occlusion, were found In the nodular lesions and also in the remaining hepatic tissues, and might be a causative factor for the nodular lesions.