Open AccessAN ETIOLOGICAL STUDY ON RENAL ADENOMAS
Author(s) -
Ohmori Takaaki,
Murata Yoshio,
Kitamura Hajime
Publication year - 1982
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1982.tb02059.x
Subject(s) - pathology , adenoma , etiology , medicine , kidney , autopsy , renal cortex
An etiological study on renal adenomas with specific references to dysplastic tubular lesions and adenocarcinomas was made, concentrating on histo‐pathological and statistical surveys. Seventy‐two unilateral kidneys obtained at random in autopsy cases were examined macro‐ and microscopically on the consecutive sliced sections. Adenomas were found frequently in the cortex of 15 cases (20.8%), and particularly dysplastic tubular lesions were considerably associated with adenomas and detected even more frequently in 26 cases (36.1%), whereas fibromas in the medulla of 8 cases (11.1%). Most of the adenomas (86.7%) were found in nephrosclerotic kidneys; i.e., in vascular nephrosclerosis (53.4%), chronic pyelonephritis (13.3%), and in end‐stage kidneys. The morphological feature of adenoma cells were also confirmed in the dysplastic tubular epithelial cells. These data imply that long‐term renovascular and/or renostromal damages may induce dysplastic tubular lesions and further act as important enhancing or promoting factors on adult renal oncogenesis from the cortical tubular epithelium.