Open AccessMALIGNANT FIBROUS HISTIOCYTOMA OF BONE ASSOCIATED WITH FOCAL HEMANGIOPERICYTOMATOUS PATTERN
Author(s) -
Terashima Kazuo,
Suda Akio,
Imai Yutaka,
Watanabe Yoshihiro,
Kasajima Takeshi,
Matsuda Mikio,
Dobashi Michio
Publication year - 1981
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1981.tb02018.x
Subject(s) - mesenchymal stem cell , pathology , pleomorphism (cytology) , pericyte , hemangiopericytoma , giant cell , lesion , tibia , ultrastructure , medicine , anatomy , biology , in vitro , immunohistochemistry , endothelial stem cell , biochemistry
A case of malignant fibrous histiocytoma of the tibia of a 49‐year‐old Japanese farmer was presented. The patient was diagnosed as malignant hemangiopericytoma by biopsy, wheseas the amputated material showed a marked pleomorphism representing features of malignant fibrous histiocytoma. Ultrastructurally, undifferentiated mesenchymal cells, intermediate cells between the undifferentiated mesenchymal cells and fibroblastic cells, fibroblastic cells and histiocytoid cells including bizarre giant cells were confirmed in a broad modulating spectrum. The hemangiopericytomatous lesion was predominated by intermediate cells, the ultrastructure of which bore a close resemblance to that of pericytes, and was regarded to be resulted from a differentiation of undifferentiated mesenchymal cells towards the pericyte.