Open AccessNEUTROPHILIC POLYMORPHONUCLEAR LEUCOCYTES IN OBESE CHILDREN
Author(s) -
Itoh Hiroshi,
Morihana Yutaka,
Cheong Wong Ki,
Misu Hideo,
Tamaki Takeo,
Suguro Tetsuo,
Hirata Yoshio
Publication year - 1981
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1981.tb01362.x
Subject(s) - pathology , medicine , immunology
In 378 obese and 35 control children, a patho‐histometric study was performed regarding the relation of the morphology of neutrophilic polymorphonuclear leucocytes(PMNL) to obesity. Sudan Black B staining studies were undertaken to compare the change In PMNL In obese and non‐obese childhood groups. The size and density of the cytoplasm of the PMNL were greater in the obese group. The average diameter of PMNL was 14.2±0.1 micra in the obese group and 13.6±0.2 in the control group. The electron microscopic feature of PMNL in the obese group included an increase In the number of the specific granules with diameter of 0.1 to 0.2 micron. These PMNL in obesity may be correlated with changes in the serum or hepatic lipid levels. An elevation of cholesterol, triglyceride, and beta‐lipoprotein in the serum was found in obese children. The hepatic function was abnormal only In advanced degree of obesity.