Open AccessCULTURE OF ISOLATED GLOMERULI FROM NORMAL AND NEPHRITIC RABBITS
Author(s) -
Morita Takashi,
Oite Takashi,
Kiaara Itaru,
Yamamoto Tadashi,
Hara Masanori,
Naka Ayako,
Ohno Shigeko
Publication year - 1980
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1980.tb03280.x
Subject(s) - pathology , receptor , intercalated cell , biology , microbiology and biotechnology , chemistry , medicine , kidney , endocrinology
The existence of four types of cells in the glomerular outgrowths from both normal and nephritic rabbits was confirmed, and their characteristics by phase contrast, scanning electron, and transmission electron microscopy are described. Type I (arborized), Type II (fusiform), Type III (round), and Type IV (paving stone‐like) cells presumably originate from visceral epithelial cells, mesangial cells, monocpes, and parietal epithelial cells of Bowman's capsule, respectively, though conclusive evidence is still lacking. The Type III cells, unlike the other types of cells, have a remarkable phagocytic capacity as well as Fc and C3 receptors.