Open AccessMORPHOLOGIC SPECTRUM OF LIVER DISEASES AMONG CHRONIC ALCOHOLICS A Comparison between Tokyo, Japan and Cincinnati, U.S.A.
Author(s) -
Karasawa Tsutomu,
Kushida Tomoko,
Shikata Toshio,
Kaneda Haruo
Publication year - 1980
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1980.tb01346.x
Subject(s) - alcoholic liver disease , alcoholic hepatitis , medicine , chronic alcoholic , incidence (geometry) , cirrhosis , gastroenterology , chronic hepatitis , chronic liver disease , hepatitis , pathology , immunology , virus , physics , optics
To deliniate the histopathological features of liver diseases seen in Japanese alcoholics, 130 Japanese alcoholic patients were studied in comparison with 238 American alcoholic patients. In Japan female alcoholic patients were extremely rare. The male to female ratio was 127 to 3 in Japan and 152 to 89 in U.S.A. Although all aspects of alcoholic liver disease did exist in Japan, typical cases of acute alcoholic hepatitis with alcoholic hyalins were remarkably smaller in number (9.2% in Japan versus 39.5% in the U.S.A.). The severity based on histopathological findings was also less in the Japanese cases. In contrast to this, 46 percent of Japanese alcoholic patients had chronic hepatitis, and the incidence of multilobular cirrhosis was much greater in Japan wherewith higher prevalence of viral hepatitides.