Open AccessGENERALIZED CYTOMEGALIC INCLUSION DISEASE IN NEONATES AND INFANTS
Author(s) -
Nakamura Yasuhiro,
Komatsu Yoshiharu,
Hosokawa Yoshiaki,
Nakashima Teruyuki,
Nakashima Nobuko,
Yano Hiroshi,
Hashimoto Takeo,
Nakashima Hirobumi,
Takeya Shigeru
Publication year - 1980
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1980.tb01329.x
Subject(s) - cytomegalic inclusion disease , pathology , disease , inclusion (mineral) , inclusion bodies , medicine , virus , virus diseases , immunology , biology , chemistry , biochemistry , mineralogy , escherichia coli , gene
Cytomegalic inclusion disease (C.M.I.) is caused by the salivary gland virus which is species‐specific, and characterized by formation of inclusion‐bearing cells in various organs. From the view point of spreading, it is divided into the localized and generalized type. We studied 18 generalized cases of infants in whom inclusion‐bearing cells were detected in more than three organs. As to the portal of entry and the time of infection, cytomegalic inclusion disease can be classified into three subgroups in infants; congenital form (2 cases), early acquired form (8 cases) and acquired form with other debilitating diseases (8 cases).