Open AccessEXTRAMEDULLARY HEMATOPOIESIS PRESENTING AS MEDIASTINAL TUMOR
Author(s) -
Tokumitsu Shinichi,
Tokumitsu Kumi,
Kohnoe Kazuhiro,
Takeya Motohiro,
Takeuchi Tadao
Publication year - 1980
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1980.tb01326.x
Subject(s) - extramedullary hematopoiesis , pathology , medicine , autopsy , rib cage , haematopoiesis , anemia , histiocyte , thoracic vertebrae , lumbar vertebrae , anatomy , lumbar , biology , stem cell , genetics
An autopsy revealed extramedullary hematopoietic foci scattered along the thoracic vertebrae and between the ribs in a patient who died of lung cancer. One of them formed a tumor‐like mass adhering to the 10th vertebra, and measured 8 × 6 × 2 cm. The cellular components included erythrocytic, granulocytic and megakaryocytic series at various stages of maturation as well as abundant iron‐pigmented histiocytes. The patient also suffered from chronic hemolytic anemia and secondary hemochromatosis. The intimate relationship of the intrathoracic tumor‐like masses of extramedullary hematopoietic tissue with chronic hemolytic anemia is briefly reviewed.