Open AccessELECTRON MICROSCOPIC STUDY ON THE PROXIMAL PORTIONS OF THE ANTERIOR CEREBRAL ARTERIES IN RATS WITH LONG‐TERM HYPERTENSION
Author(s) -
Kojimahara Masayasu,
Ooneda Genju
Publication year - 1979
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1979.tb03173.x
Subject(s) - adventitia , basement membrane , vacuole , vesicle , pathology , anatomy , homogeneous , chemistry , smooth muscle , electron microscope , cerebral arteries , biology , membrane , medicine , cytoplasm , endocrinology , biochemistry , physics , optics , thermodynamics
Proximal portions of the anterior cerebral arteries in rats with long‐term hypertension were electron microscopically studied. The abnormal substances such as granules, vesicles, vacuoles and other membranous structures, relatively homogeneous masses, and basement membrane‐like substances were observed around the medial smooth muscle cells. Basement membrane‐like substances were increased with advancing age and the majority of these substances are thought to be turned from the granulo‐vesicles. Abnormal substances deposited in the media are thought to be “hyalino‐fibrous materials”. The majority of our materials had a clear‐cut border between the media and the adventitia. The subendothelial spaces were slightly distended with fibrillar and/or finely granular substances with age, but neither cellular element nor fibrinoid substance was found in them.