Open AccessRHEUMATOID ARTHRITIS WITH SYSTEMIC NECROTIZING ARTERITIS
Author(s) -
Koizumi Fumitomo,
Pukase Masayuki,
Wakaki Kunihiko
Publication year - 1979
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1979.tb00948.x
Subject(s) - arteritis , medicine , rheumatoid arthritis , pathology , fibrinoid necrosis , necrotizing vasculitis , vasculitis , systemic vasculitis , immunology , disease
An autopsy case of rheumatoid arthritis with active polyarthritis, systemic necrotizing arteritis, pleuritis, pericarditis, rheumatoid nodules in a few organs and a healing gastric ulcer was reported. Histologically, systemic necrotizing arteritis was characterized by vascular changes of the following three types: Granulomatous arteritis with a characteristic arrangement of mesenchymal cells forming a palisade around coagulation necrosis of media and some of them formed a rheumatoid nodule‐like lesion in the wall (RA type); Fibrinoid arteritis very similar to the Kussmaul‐Maier type periarteritis nodosa (PN type); and chronic arteritis with endarterial proliferation (Ep type). Although it is hard to distinguish arteritis of PN type from the Kussmaul‐Maier type periarteritis nodosa, arteritis of RA type with rheumatoid nodule‐like lesion in the wall may be interpreted as an extremely developed form of vasculitis in rheumatoid arthritis.