Open AccessNATURALLY OCCURRING ANGIOSARCOMA OF THE TIBIA IN AN NZB MOUSE
Author(s) -
Inada Osamu,
Yumoto Tokichi
Publication year - 1978
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1978.tb01253.x
Subject(s) - angiosarcoma , tibia , pathology , hemangiosarcoma , medicine , anatomy
An osteolytic bone tumor was found in a 12‐month‐old male NZB mouse. Macroscopically and histologically this tumor was angiosarcoma originating in bone with distant metastasis present in the spleen. The primary tumor was successfully transplanted in the back subcutaneous tissue of syngeneic mice, and the characteristics of the transplants, were found to be similar to those of the primary tumor. The ultrastructure of tumor is described.