Open AccessA STUDY ON THE MELANIN‐LADEN DENDRITIC CELL (MELANOCYTE) IN OVARIAN CYSTIC TERATOMA
Author(s) -
Shibata Toshikatsu,
Mori Wataru
Publication year - 1978
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1978.tb00534.x
Subject(s) - melanocyte , teratoma , pathology , melanin , ovary , biology , epithelium , ovarian teratoma , mature cystic teratoma , anatomy , medicine , melanoma , endocrinology , cancer research , genetics
To confirm the existence and to analyse the distribution of the melanocyte in cystic teratoma of the ovary, 51 cases were collected, among which 47 were found suitable for gross and histological examinations. The tissue components of cystic teratoma where the melanocyte was seen more or less associating were; the squamous, cuboidal and columnar cell epithelia especially the epidermal epithelium, the brain tissue principally the leptomeninx, and the interstltium. The frequency of melanocytes’association in the respective tissue was shown and compared between each other. One thing which was quite interesting for us was the relationship between the existence of brain tissue and the development of melanocyte in cystic teratoma. The melanocyte appeared in the above tissues, especially the Interstltium, of cystic teratoma more frequently when the brain tissue was coexisting in the same tumor. These findings seem to be of meaningful suggestions concerning the melanocy‐togenesis not only of cystic teratoma of the ovary, but also in a physiological condition in man.