Open Access— Scanning Electron Microscopic Observation of Amyloid‐Laden Mouse Liver —
Author(s) -
Takahashi Mutsuo
Publication year - 1977
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1977.tb03037.x
Subject(s) - amyloidosis , cytoplasm , perisinusoidal space , pathology , amyloid (mycology) , scanning electron microscope , electron microscope , amyloid fibril , kupffer cell , chemistry , fibril , biology , biophysics , anatomy , amyloid β , microbiology and biotechnology , hepatocyte , medicine , materials science , biochemistry , physics , optics , disease , in vitro , composite material
Amyloidosis of liver in mice induced by casein injection was studied by scanning electron microscopy (SEM). In the fractured‐surfaces of the central portion of amyloid nodules, they appeared as chestnut‐bur‐like structures and were composed of numerous thread‐like structures of fasciculated amyloid fibrils and of stick‐like structures of amyloid bundles in three dimensional figure. In the cytoplasm of the Kupffer cell, amyloid bundles were revealed as band‐like bulges. These bulges were projected from the Kupffer cell into the Disse's space and continued with thread‐like structures outside the cytoplasm of Kupffer cells. ACTA PATH. JAP. 27: 809‐822, 1977.