Open AccessULTRASTRUCTURAL CHANGES OF THE DOG MYOCARDIUM IN EXTRACORPOREAL CIRCULATION
Author(s) -
Kajihara Hiroki,
Yokoro Kenjiro,
Iijima Soichi,
Mochizuki Takaaki,
Taguchi Kazumi
Publication year - 1977
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1977.tb00166.x
Subject(s) - myofibril , ventricle , extracorporeal circulation , left ventricles , contraction (grammar) , ultrastructure , medicine , cardiac muscle , anatomy , myocyte , cardiology , cardiac ventricle , pathology
The effects of the cardiopulmonary bypass circulation on the cardiac muscle cells were studied electron microscopically. Subendocardial hemorrhage was commonly recognized in both ventricles. However, it appeared earlier and more severely in the right ventricle than In the left ventricle. Clear flocculent areas containing numerous filamentoue structures were originated from degradation of myofibrils. Degradation of myofibrils occurred within 1 hour after bypass circulation. Degenerative changes of myocardial cells such as zonal lesions, contraction bands and swelling or condensation of mitochondria appeared in both ventricles. Damages of myocardial cells In right ventricular wall were more severer as compared with those in the left throughout the period of observation. ACTA PATH. JAP. 27: 435–445, 1977.