Open AccessFINE STRUCTURES OF THE SPLEEN IN HEREDITARY ELLIPTOCYTOSIS
Author(s) -
Matsumoto Noboru,
Ishihara Tokuhiro,
Takahashi Mutsuo,
Uchino Fumiya,
Ono Junichiro,
Miwa Shiro,
Kiyomitsu Yoshinori
Publication year - 1976
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1976.tb00510.x
Subject(s) - hereditary spherocytosis , spleen , spherocytosis , pathology , pathogenesis , anemia , hemolytic anemia , medicine , biology , immunology , genetics , splenectomy
Light and electron microscopic studies of the spleen and liver from a patient with hereditary elliptocytosis have been reported. Characteristic findings are congestion of the cordal space, diminished variation of the erythrocyte shape In the cord, relatively empty sinuses and erythrophagocytosis by the cordal macrophages. The same basic defect of the red cell membrane as has been documented in hereditary spherocytosis might be a possible explanation on the pathogenesis of this rare hemolytic anemia.